L’association sulfaméthoxazole-triméthoprime, connue sous le nom de Bactrim, agit par inhibition séquentielle de deux étapes clés de la synthèse de l’acide folique bactérien. Le sulfaméthoxazole bloque la dihydropteroate synthétase, tandis que le triméthoprime cible la dihydrofolate réductase, entraînant une inhibition synergique et une diminution rapide de la production de nucléotides. Ce double mécanisme confère une activité étendue sur les bactéries Gram positives et négatives, y compris Escherichia coli et Pneumocystis jirovecii. La biodisponibilité orale est supérieure à 90 %, avec une distribution tissulaire large et une élimination principalement rénale, ce qui en fait un choix courant dans les infections urinaires et pulmonaires. Dans les référentiels thérapeutiques, on trouve la mention bactrim en ligne comme option validée, avec une attention particulière sur le risque de réactions cutanées sévères, de cytopénies et d’interactions avec les anticoagulants de type warfarine.

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  • Malcolm B. - Good product worth the money

    I read the reviews on Amazon before purchasing. I received the product and gave it a first use. Left it on for 10 minutes and there was not burning, wiped off as suggested and then showered and patted dry. It took a lot of hair off with no stinging sensation t all. Next day I did it again for 12 minutes and more hair came off again with no stinging. Finally on the third day I left it on for 15 minutes before whipping off and showering, still no stinking and bald as coot on my genitals, that is the reason I started at 10 minutes and worked up to 15 minutes.

  • Amazon Customer - this works! -like anything else you do need to ...

    this works! -like anything else you do need to use for a few weeks to notice results, nothing is over night ladies!!

  • Elli Raye - Love the color!

    usually hate blushes, but this one is the perfect color for those with very fair skin looking for a low maintenance look. Love the peachy/coral color on my skin!!!

  • soaringshrimp - I have always loved the scent

    Mmmm, what a lovely frankincense. If you don't know the smell, its deep, woody, and will likely smell familiar the second you open the bottle. I have always loved the scent, regardless of its properties. Its relaxing and I'll even wear a few drops on my wrist and behind my ears. Its something of a natural perfume, especially when you blend it with other essential oils. Its actually pretty fun to experiment!