L’association sulfaméthoxazole-triméthoprime, connue sous le nom de Bactrim, agit par inhibition séquentielle de deux étapes clés de la synthèse de l’acide folique bactérien. Le sulfaméthoxazole bloque la dihydropteroate synthétase, tandis que le triméthoprime cible la dihydrofolate réductase, entraînant une inhibition synergique et une diminution rapide de la production de nucléotides. Ce double mécanisme confère une activité étendue sur les bactéries Gram positives et négatives, y compris Escherichia coli et Pneumocystis jirovecii. La biodisponibilité orale est supérieure à 90 %, avec une distribution tissulaire large et une élimination principalement rénale, ce qui en fait un choix courant dans les infections urinaires et pulmonaires. Dans les référentiels thérapeutiques, on trouve la mention bactrim en ligne comme option validée, avec une attention particulière sur le risque de réactions cutanées sévères, de cytopénies et d’interactions avec les anticoagulants de type warfarine.

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  • Sherri - works well. quite fast.

    I received this in good order with no signs of flaws or damage. I ordered this for an upgrade project on my main system to use as a cache drive. As that machine is still being built I tested it on the one it will be replacing. The installation is straight up for anyone that has installed a drive. For most PC's you will of course need some sort of mount or adaptor to properly install the 2.5" drive. In my case it is mounted in an expansion slot frame. Drive recognized with no problems and functioned as expected. The performance difference between this drive and a "classic" HDD is quite noticeable and not at all unexpected with this drive being much faster. There are several ways to use drives of this type and speed, but the purpose I discussed previously is the one I have chosen. A cache drive to boost standard HDD performance.

  • Michael1951 - Total crap

    It says multi device but don't you believe it. Unless, of course/ you have five PCs and no mobile devices. It can't recognize any of my tablets or phones and their all running on the latest android. Trying to work with their online people is like trying to pull teeth through a straw. Now when I go to my management they have mobile turned off, or at least there's a red sign on it and I can't use it. This is how I'm treated after being a loyal Norton customer for over 20 years.