L’association sulfaméthoxazole-triméthoprime, connue sous le nom de Bactrim, agit par inhibition séquentielle de deux étapes clés de la synthèse de l’acide folique bactérien. Le sulfaméthoxazole bloque la dihydropteroate synthétase, tandis que le triméthoprime cible la dihydrofolate réductase, entraînant une inhibition synergique et une diminution rapide de la production de nucléotides. Ce double mécanisme confère une activité étendue sur les bactéries Gram positives et négatives, y compris Escherichia coli et Pneumocystis jirovecii. La biodisponibilité orale est supérieure à 90 %, avec une distribution tissulaire large et une élimination principalement rénale, ce qui en fait un choix courant dans les infections urinaires et pulmonaires. Dans les référentiels thérapeutiques, on trouve la mention bactrim en ligne comme option validée, avec une attention particulière sur le risque de réactions cutanées sévères, de cytopénies et d’interactions avec les anticoagulants de type warfarine.

www.londonroad-medicalpractice.nhs.uk Review:

London Medical Practice - Information about the doctors surgery opening hours, appointments, online prescriptions, health information and much more - London Medical Practice London Medical Practice,Aspen Centre,Horton Road,Gloucester GL1 3PX, Information about the doctors surgery opening hours, appointments, online prescriptions, health information and much more

http://www.londonroad-medicalpractice.nhs.uk/opening-times.aspx London Medical Practice - Doctors surgery opening times and what to do when we are closed - London Medical Practice - Doctors surgery opening times and what to do when we are closed

http://www.londonroad-medicalpractice.nhs.uk/making-appointments.aspx London Medical Practice - How to make an appointment to see your doctor or nurse at the surgery - London Medical Practice - How to make an appointment to see your doctor or nurse at the surgery

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http://www.londonroad-medicalpractice.nhs.uk/clinics-and-services.aspx London Medical Practice - The clinics and other services offered by our doctors surgery - London Medical Practice - The clinics and other services offered by our doctors surgery

http://www.londonroad-medicalpractice.nhs.uk/new-patients.aspx London Medical Practice - Information for new patients wishing to join the doctors surgery - London Medical Practice - Information for new patients wishing to join the doctors surgery

http://www.londonroad-medicalpractice.nhs.uk/ppg.aspx Patient Participation Group - London Medical Practice,London Medical Practice,Aspen Centre,Horton Road,Gloucester,GL1 3PX,doctors London Medical Practice,doctors Aspen Centre,doctors Horton Road,doctors Gloucester,gp,GP,doctor,doctors,medical centre,health centre,mysurgerywebsite,surgery website,nurse,practice,dentist,dentists,dental

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City: -0.1224 , United Kingdom

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