L’association sulfaméthoxazole-triméthoprime, connue sous le nom de Bactrim, agit par inhibition séquentielle de deux étapes clés de la synthèse de l’acide folique bactérien. Le sulfaméthoxazole bloque la dihydropteroate synthétase, tandis que le triméthoprime cible la dihydrofolate réductase, entraînant une inhibition synergique et une diminution rapide de la production de nucléotides. Ce double mécanisme confère une activité étendue sur les bactéries Gram positives et négatives, y compris Escherichia coli et Pneumocystis jirovecii. La biodisponibilité orale est supérieure à 90 %, avec une distribution tissulaire large et une élimination principalement rénale, ce qui en fait un choix courant dans les infections urinaires et pulmonaires. Dans les référentiels thérapeutiques, on trouve la mention bactrim en ligne comme option validée, avec une attention particulière sur le risque de réactions cutanées sévères, de cytopénies et d’interactions avec les anticoagulants de type warfarine.

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  • Amazon Customer - Subpar Hi-Top

    These shoes are definitely a far cry from my older B-Ball Shoes. The sole in particular leaves a lot to be desired. I will say to the "Pro" side of things that they are nice looking shoes. No qualms about that. However, that is not on the top of my list by any means. The unfortunate "Bad"...poor traction on the court, very poor. Night and day difference from my much older and more worn Nike. Very disappointing. Second, the sole itself is not cushioned well. I'm not talking about the insole here. That can be remedied easy enough with an insert. My aging Nike's fell apart after years of hanging around. You can see why they were better for comfort as well. I cannot recommend these to anyone looking to play competitive basketball. Fortunately, I'm just a coach so a little slip sliding away is not a big deal. My suggestion is to look elsewhere. Take it for what it is worth.

  • Sara Sherman - I'd buy again.

    I like it but actually would like the packets to be half the size. Feel as though I'm using way too much product for the things I've used it for. Would rather have smaller and more packages in a set so I could scale as needed. I've only used it to repair frayed charging cables, and it works well though any that still bend will crack the material.

  • andrea - Love my isosensual

    I have desired the perfect butt for so long, as a curvy woman I desire every part of my body to be even with one another to feel complete, after having kids back to back I somehow lost that perfect feeling, I let myself go , now it's been almost two years since I've given birth and for the last 3 months I have gone beyond all strength to get back my curvy butt and body, I searched every possible butt enhancing product and finally I came across isosensual butt enhancement I did readers hobby this product and read every review there is for 2 months straight and was scared that it was another product ppl claim to work. When I tell you this stuff is the real deal, I mean I've managed to Knock Nikki Manaj out of the ball park, the difference is my booty is natural it's permanent, Thanks to isosensual, I love this product , and this product will forever be one that I will use as long as it exists! I recommend this to any women looking to boost or get a bigger butt!!!! Ps my husband will not keep his eyes off my apple bottom!!! Isosensual is my new best friend!