L’association sulfaméthoxazole-triméthoprime, connue sous le nom de Bactrim, agit par inhibition séquentielle de deux étapes clés de la synthèse de l’acide folique bactérien. Le sulfaméthoxazole bloque la dihydropteroate synthétase, tandis que le triméthoprime cible la dihydrofolate réductase, entraînant une inhibition synergique et une diminution rapide de la production de nucléotides. Ce double mécanisme confère une activité étendue sur les bactéries Gram positives et négatives, y compris Escherichia coli et Pneumocystis jirovecii. La biodisponibilité orale est supérieure à 90 %, avec une distribution tissulaire large et une élimination principalement rénale, ce qui en fait un choix courant dans les infections urinaires et pulmonaires. Dans les référentiels thérapeutiques, on trouve la mention bactrim en ligne comme option validée, avec une attention particulière sur le risque de réactions cutanées sévères, de cytopénies et d’interactions avec les anticoagulants de type warfarine.

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  • Jo Jo the Dogfaced Boy - 10 years of use is proof enough for me!

    I have been using Bona Hardwood Floor Cleaner for 10 years now on our Brazilian Cherry floors. For the money you can't beat the 128 Ounce refill bottle. Bona Cleaner works great leaving no residue. I use it with a floor pad once a week. I have never used polish on our floors and they look as good as they did the day I installed them. Remember to wash your application/cleaning pad every couple of floor cleanings for best results. One of the best things we ever did to keep our floors and house looking good was to stop wearing shoes in the house. We only wear socks or slippers inside.

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    I would not use any other program! Over the years I've used them all and would not go back if you paid me! Kaspersky is one program where the others are a group of programs i.e.firewas, anti-virus etc. Kaspersky runs in the background and does bot eat up RAM like others. It checks for new bad programs once every hour! It is checking all the programs and files on your computer every minute you booted up! It is keeping you safe . . . end of story! ! !

  • francisco - its not that durable

    i thought it was kind of good but its not that durable it gets scratched pretty easy so i much prefer a wodden one like the ouija frow winning moves or just make your own go to home depot and buy a piece of wood you can desing it how ever u like

  • krahn - Great purchase.

    Great price. Works well and doesn't leak. Install was doable but challanging for a DIY install. Saved me over $300 to DIY.

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    I can certainly related to all the 20 plus posted comments about this product both good and bad . I too suffer from post acne, large pores, and oily skin. The first time I tried BareMinerals I was like a few of you, couldnt see a difference, didnt know if I was putting it on right, didnt have the right color (being that I am a woman of color) thought it was a was of money. And you know what I threw away the first foundation jar never to buy it again, until I saw the infomerical about the product and of course, a shopping channel that will remain nameless that sells this particular product. So I decided to try one more time. What made me a believer the second time around was that I made sure of a few things:

  • Tab McBlane - Awesome knife

    Very cool and useful knife! I bought the pilot and the co pilot. I carry the co pilot on my life vest and the pilot on me. Only downside is the sheath latch won't fit on a wide belt. Fits great on a life vest but a challenge to get it on. Certainly won't fall off!