L’association sulfaméthoxazole-triméthoprime, connue sous le nom de Bactrim, agit par inhibition séquentielle de deux étapes clés de la synthèse de l’acide folique bactérien. Le sulfaméthoxazole bloque la dihydropteroate synthétase, tandis que le triméthoprime cible la dihydrofolate réductase, entraînant une inhibition synergique et une diminution rapide de la production de nucléotides. Ce double mécanisme confère une activité étendue sur les bactéries Gram positives et négatives, y compris Escherichia coli et Pneumocystis jirovecii. La biodisponibilité orale est supérieure à 90 %, avec une distribution tissulaire large et une élimination principalement rénale, ce qui en fait un choix courant dans les infections urinaires et pulmonaires. Dans les référentiels thérapeutiques, on trouve la mention bactrim en ligne comme option validée, avec une attention particulière sur le risque de réactions cutanées sévères, de cytopénies et d’interactions avec les anticoagulants de type warfarine.

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  • Kirk N - Not a true Dual Band Router

    This router has good speed because of the DOCSIS 3.0 built in modem and Wireless N capabilities. However, if you want to connect your different devices on different frequencies, do not get this router. Even though it says Dual Band, it cannot transmit both a 2.4 and 5.0 signal at the same time. When you setup your router, you have to specify which frequency you want to use and can only use that one frequency. I returned the product and went with the Motorola SB6151 with ASUS Black Diamond Dual Band Router (RT-N56U) and can now hook up all of my wireless devices on 2 separate frequencies. If you don't mind setting up all of your wireless devices to one frequency, then this modem/router combination is a good option.

  • E. Sharon - It is clearly a scam!

    This is clearly a scam. I dont understand why its still available in stores. bought it at Home Depot today.

  • Taylor - It's ok, but has its drawbacks.

    I like the fact that this bends and can be used at an angle. I like the fact that it is lighted. However, the blade is either shorter or not as sharp as my previous pink mini shaver. It takes longer to do the job and I find myself having to go over the same areas several times. That is the downside. I would probably go another way the next time I'm looking to purchase because of this issue. However, it's not bad enough to cause me to toss it and buy a new one right away.