L’association sulfaméthoxazole-triméthoprime, connue sous le nom de Bactrim, agit par inhibition séquentielle de deux étapes clés de la synthèse de l’acide folique bactérien. Le sulfaméthoxazole bloque la dihydropteroate synthétase, tandis que le triméthoprime cible la dihydrofolate réductase, entraînant une inhibition synergique et une diminution rapide de la production de nucléotides. Ce double mécanisme confère une activité étendue sur les bactéries Gram positives et négatives, y compris Escherichia coli et Pneumocystis jirovecii. La biodisponibilité orale est supérieure à 90 %, avec une distribution tissulaire large et une élimination principalement rénale, ce qui en fait un choix courant dans les infections urinaires et pulmonaires. Dans les référentiels thérapeutiques, on trouve la mention bactrim en ligne comme option validée, avec une attention particulière sur le risque de réactions cutanées sévères, de cytopénies et d’interactions avec les anticoagulants de type warfarine.

informatics.bidmc.org Review:

Clinical Informatics Training Program - Beth Israel Deaconess Medical Center (BIDMC) Clinical Informatics ACGME Fellowship Training Program, Boston MA, Harvard Medical School

  • http://informatics.bidmc.org/about Overview | Clinical Informatics Training Program - The Division of Clinical Informatics has a rich educational offering for students and fellows. The Division runs an ACGME accredited fellowship program in clinical informatics, available for physicians who have completed a residency program and wish to specialize in informatics. 
  • http://informatics.bidmc.org/history History | Clinical Informatics Training Program - The Division of Clinical Informatics, created over 40 years ago by Drs. Howard Bleich and Warner Slack, was among the first academic divisions in the world to concentrate on the use of computers for patient care, teaching, and medical research. The goals of the Division have been to improve the quality and reduce the cost of medical care, to enhance the quality of medical education, to improve the relationship between doctor and patient, and to explore innovative approaches to research through computing.
  • http://informatics.bidmc.org/medical-students Medical Students | Clinical Informatics Training Program - Division faculty teach and mentor medical students across all phases of their training. Division faculty welcome medical students during their elective time in their fourth or fifth years, as well as summer projects and Scholars in Medicine projects.
  • http://informatics.bidmc.org/programs-industry Programs For Industry | Clinical Informatics Training Program - The Division of Clinical Informatics is one of the oldest academic and research groups focused on the effective use of information and communication technologies in patient care. Our faculty has developed hospital-wide clinical computing systems at the Beth Israel Deaconess Medical Center and the Brigham and Women’s Hospital. Our faculty were the very first to engage patients in direct dialogue with computers and been building and evolving clinical decision support systems for four decades.
  • http://informatics.bidmc.org/getting-here Getting Here | Clinical Informatics Training Program - Directions The Division of Clinical Informatics is located in Coolidge Corner, about one mile west of the Longwood Medical Area.
  • http://informatics.bidmc.org/news/supporting-decision-support-2nd-year-fellow-dr-mujeeb-basit-detects-cds-rule Supporting Decision Support - 2nd Year Fellow Dr. Mujeeb Basit Detects CDS Rule Failures | Clinical Informatics Training Program - At AMIA 2015, Dr. Mujeeb Basit presented his work on using data visualization to detect defects in clinical decision support rules. ---
  • http://informatics.bidmc.org/news/fellow-team-wins-brigham-openepic-hackathon Fellow Team Wins Brigham Open.Epic Hackathon | Clinical Informatics Training Program - Congrats to Dr. Mujeeb Basit and his team that won the most recent hackathon at BWH using open.epic.  The team drew from early work from Division co-founder Howard Bleich and created an application that helped interpret the complexities of arterial blood gas results using FHIR and Open Epic.  From MIT's Hacking Medicine :: http://mithackmed.com/post/133211657924/2015-brigham-hackathon-attracts-...
  • http://informatics.bidmc.org/news/dci-faculty-speak-primary-care-innovations-conference DCI Faculty speak at Primary Care Innovations Conference | Clinical Informatics Training Program - DCI chief Charlie Safran moderated a discussion with Dr. Brad Crotty (from DCI) and Dr. Tom Agresta, the informatics lead at the Connecticut Institute for Primary Care, on the role of technology in primary care improvement. Topics included patient-generated data, telemedicine and e-visits, and team-based communication. The panel reminded the audience that technology can not solve problems in process, and the group discussed how best to try and implement new technology in primary care delivery.
  • http://informatics.bidmc.org/news/dr-safran-delivers-medical-grand-rounds-infosage-healthware-patients-and-families Dr. Safran Delivers Medical Grand Rounds on InfoSAGE - Healthware For Patients and Families | Clinical Informatics Training Program - Charlie Safran delivered medical grand rounds detailing InfoSAGE, and work towards providing informatics tools beyond the doctor and health system level to a community level. Dr. Safran was recently promoted to Professor of Medicine at Harvard Medical School. 

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  • Grit Lit - Finally!

    At last there's a reason to get back on board with the Best American Essays! I had stopped picking up annual volumes of this series as there seemed to be too many esoteric pieces of interminable length and no point. But Cheryl Strayed, this year's editor, did a great job choosing essays that aren't just "think pieces" but where people live interesting lives, act and change. The essays are beautifully written and some bring tears. If you've never tried this series, start here.

  • Charile - One of the best shows on tv!

    I love this show! I can really relate to the struggles they go through because I have been there myself.

  • Haily Radnor - Great Ball

    Great all around indoor ball. The grip allows me to set the ball fairly descent; additionally I can get a really good standing floater serve in. The only thing that concerns me is that I do have to check the PSI before every use. It does seem to require some air more often than not; but then again this is my first ball I've ever purchased so I don't know if all balls require that or not. Either way, this is my go to ball.

  • Rick Kattreh - What a horrible device. 5 test strips later and still not ...

    What a horrible device. 5 test strips later and still not a reading. I have the app and the device. First time out of the box and many hoops to jump through I was able to get a reading. Next morning the only thing this device could do was show the round swirly thing. Tried everything to try and get a reading. 5 test strips later and a lot of frustration, rechecked the instructions. Nothing on problems with a meter not taking input. However if you want to learn how to put a plastic sanitary bag over your phone there's an entire page dedicated to that. Absolutely unbelievable. Stay away from this device.