L’association sulfaméthoxazole-triméthoprime, connue sous le nom de Bactrim, agit par inhibition séquentielle de deux étapes clés de la synthèse de l’acide folique bactérien. Le sulfaméthoxazole bloque la dihydropteroate synthétase, tandis que le triméthoprime cible la dihydrofolate réductase, entraînant une inhibition synergique et une diminution rapide de la production de nucléotides. Ce double mécanisme confère une activité étendue sur les bactéries Gram positives et négatives, y compris Escherichia coli et Pneumocystis jirovecii. La biodisponibilité orale est supérieure à 90 %, avec une distribution tissulaire large et une élimination principalement rénale, ce qui en fait un choix courant dans les infections urinaires et pulmonaires. Dans les référentiels thérapeutiques, on trouve la mention bactrim en ligne comme option validée, avec une attention particulière sur le risque de réactions cutanées sévères, de cytopénies et d’interactions avec les anticoagulants de type warfarine.

gp2u.com.au Review:

Online Doctor Service | GP2U Telehealth Australia - The GP2U online doctor service provides safe convenient consultations with Australian GPs and Specialists. Prescription medications and certificates available.

  • https://gp2u.com.au/faq/gp2u_what_we_do.html GP2U - What We Do - GP2U - What we do to make Telehealth a practical reality. Features and Benefits. Products and Services.
  • https://gp2u.com.au/about_us.html About Us - GP2U Telehealth is an Australian company specialising in managing Telehealth logistics

    Country: 101.234.74.4, Oceania, AU

    City: 149.2101 New South Wales, Australia

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