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Home - Current Protocols - Current Protocols comprises more than 17,000 regularly updated, peer reviewed, and indexed scientific techniques and procedures across 17 life science disciplines.

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  • http://currentprotocols.com/WileyCDA/CPUnit/refId-cpns12.html Pica in Rats as a Preclinical Model of Emesis - Current Protocols - The ability to assess the potential for gastrointestinal adverse events in a preclinical setting is a challenge in the development of new drugs, as the vast majority of in vivo research is conducted in rodent species lacking a vomiting reflex
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  • http://currentprotocols.com/WileyCDA/CPUnit/refId-cpns14.html Cigarette Smoke Extract: A Preclinical Model of Tobacco Dependence - Current Protocols - Animal models are used to study many human diseases, one of which is tobacco addiction
  • http://currentprotocols.com/WileyCDA/CPUnit/refId-cpns15.html The Neonatal Ventral Hippocampal Lesion (NVHL) Rodent Model of Schizophrenia - Current Protocols - Animal models are crucial to the study of the neurobiological bases of psychiatric disorders, but schizophrenia is a particularly challenging disorder to model given the complexity and heavily verbal nature of its symptoms
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  • http://currentprotocols.com/WileyCDA/CPUnit/refId-mb0427.html Strand‐Specific Transcriptome Sequencing Using SMART Technology - Current Protocols - Next‐generation sequencing is empowering a deeper understanding of biology by enabling RNA expression analysis over the entire transcriptome with high sensitivity and a wide dynamic range
  • http://currentprotocols.com/WileyCDA/CPUnit/refId-mb0728.html Preparation of Low‐Input and Ligation‐Free ChIP‐seq Libraries Using Template‐Switching Technology - Current Protocols - Chromatin immunoprecipitation (ChIP) followed by high‐throughput sequencing (ChIP‐seq) has become the gold standard for mapping of transcription factors and histone modifications throughout the genome
  • http://currentprotocols.com/WileyCDA/CPUnit/refId-mb2705.html Protein Interaction Profile Sequencing (PIP‐seq) - Current Protocols - Every eukaryotic RNA transcript undergoes extensive post‐transcriptional processing from the moment of transcription up through degradation
  • http://currentprotocols.com/WileyCDA/CPUnit/refId-mb2807.html Isolation of Primary Fibroblast Culture from Wildlife: the Panthera onca Case to Preserve a South American Endangered Species - Current Protocols - Cell line establishment of somatic cells is a valuable resource to preserve genetic material of rare, difficult‐to‐find, endangered and giant species like Jaguar (Panthera onca), the largest South American felid
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