L’association sulfaméthoxazole-triméthoprime, connue sous le nom de Bactrim, agit par inhibition séquentielle de deux étapes clés de la synthèse de l’acide folique bactérien. Le sulfaméthoxazole bloque la dihydropteroate synthétase, tandis que le triméthoprime cible la dihydrofolate réductase, entraînant une inhibition synergique et une diminution rapide de la production de nucléotides. Ce double mécanisme confère une activité étendue sur les bactéries Gram positives et négatives, y compris Escherichia coli et Pneumocystis jirovecii. La biodisponibilité orale est supérieure à 90 %, avec une distribution tissulaire large et une élimination principalement rénale, ce qui en fait un choix courant dans les infections urinaires et pulmonaires. Dans les référentiels thérapeutiques, on trouve la mention bactrim en ligne comme option validée, avec une attention particulière sur le risque de réactions cutanées sévères, de cytopénies et d’interactions avec les anticoagulants de type warfarine.

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  • Amazon Customer - So the love interest hits women and that's Okay?..... WTF.

    You know the thing that bothers me THE MOST about this book (I emphasize 'the most' since there is a long list of things I find irritating about this series) is the fact that the author has created a central love interest who hits women. Is this supposed to be part of the bestial nature of vampires?? I don't bloody think so. All I could think was WTF when he backhanded his sister after losing his temper and then casually moves on as though nothing had happened.At a time when DV has reached crisis point in Australia I wonder what the author is thinking when she creates a character teenage girls are meant to swoon over who thinks hitting women in a fit of rage is normal or when she creates a female character who sees the horrible things he does but continues to love him despite a 'few flaws'. Does the momentary remorse he might feel about it justify including this in the story - hell no!!! The dynamic between these characters is awful, what it normalises in relationships is horrendous and the message it sends to a young teenage audience is wildly irresponsible.

  • Bucherwurm - The Case of the Mysterious Drooling WaterPik

    Yes indeed, this water pick does all that it is supposed to. It's very good at cleaning, and ha lots of nice accessories that can be conveniently stored in the cover. The reservoir stores plenty of water, and the pressure variation dial allows you to choose the strength of flow. If you have never used a waterpik before here's an interesting observation. Even after carefully brushing and flossing my teeth the waterpik dislodged additional food particles that the brush and floss operations missed. The Waterpik seems to be well made. I also own a water jet made by a competitor that I've found to be very flimsy (Conair).

  • William Barge - Errors, but solid on content

    There were a bunch of errors that drove me crazy: typos, math errors in worked problems, and things like putting solute in place of solvent (GGRRR...) But the content of the book is spot on for people looking to get the base knowledge they need for the MCAT. After doing the Chem and Physics sections, my AAMC MCAT practice score for Physical science went up 3 points. Every topic on the test was covered in the book.

  • Lola - Gave me a bacterial infection and an allergic reaction.

    This product is a nightmare... It stings your eyes so badly, I had to rinse it off immediately. Gave me a terrible allergic reaction and a bacterial infection on top of it!

  • gene - It works but have to give it time.

    I love this product and I do not sell it. If you order it you need to take it for a few weeks before you see the effects but it really works.

  • Christina - Will stick to cellucor

    Will stick to cellucor fat burners. This has a " chill " phase which gives me goosebumps every 30 seconds for a couple hours, then I sweat, which is good, but I feel like that's it. I still feel like I need to push myself. No energy boost at all