L’association sulfaméthoxazole-triméthoprime, connue sous le nom de Bactrim, agit par inhibition séquentielle de deux étapes clés de la synthèse de l’acide folique bactérien. Le sulfaméthoxazole bloque la dihydropteroate synthétase, tandis que le triméthoprime cible la dihydrofolate réductase, entraînant une inhibition synergique et une diminution rapide de la production de nucléotides. Ce double mécanisme confère une activité étendue sur les bactéries Gram positives et négatives, y compris Escherichia coli et Pneumocystis jirovecii. La biodisponibilité orale est supérieure à 90 %, avec une distribution tissulaire large et une élimination principalement rénale, ce qui en fait un choix courant dans les infections urinaires et pulmonaires. Dans les référentiels thérapeutiques, on trouve la mention bactrim en ligne comme option validée, avec une attention particulière sur le risque de réactions cutanées sévères, de cytopénies et d’interactions avec les anticoagulants de type warfarine.

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  • Ryan - Excellent resource

    I definitely would not have gotten the score I needed without this book. I think it gives you pretty much everything you need to do well on the GRE. The online / practice test component is priceless.

  • A. Baston - Works very, very well.- (However, Please see UPDATE of review)

    UPDATE: 6-27-10 - I still agree with everything I wrote below as far as what an outstanding product Wet & Forget is - HOWEVER, One must wear a mask when spraying this product - It will make you feel sick. if the winds blows up and you get a mouthful or even just light spraying and sucking down the vapors....A few hours after spraying, it'll zaps you of all energy, as well as light-headedness and rummy stomach aching, you'll feel like just lying in bed for a day or two - I would absolutely recommend a breathing mask of some type for any spaying with this product, even light spraying. Wet & Forget is a great product as I described below, but I had to deducted a star for the obvious toxicity that it fails to mention on the label.

  • TrashOfAmerica - ... the glow in the dark effect would be a nice added touch

    I thought the glow in the dark effect would be a nice added touch. I didn't know the planchette takes batteries! What a joke! Do not buy this.

  • Tammy - lotion

    at first it worked very well, but i realize that my skin got more sensitive using it, so i stopped using this lotion